Research
My areas of interest in research have undergone some swings. Artificial Neural Networks was the beginning point, for some time it centred around Image processing. I have also been a co-supervisor with my mentor and Professor, Dr K P P Pillai in two works in Electrical Engineering, involving Finite Element Methods in electromechanical field analysis. Like wise, I guide one study each in Malayalam Speech Processing and also Holographic Memories. Of late I have narrowed down to specific topics and no longer attempt to have one-off other interests. The areas are:
1.Genomic/Proteomic Signal Processing (Application of DSP to analyse gene and amino acid sequences, investigations using Fourier, Wavelet and Fractal/Lacunarity analysis and also entropy measures). Specific problems studied include gene finding, protein sub-cellular localization etc. Await a list of classic references in GSP.
2. DNA/Protein Sequence Compression. Await a list of classic references in this area.
3. Applications of Principal Component Analysis (PCA) and Non-negative Matrix Factorisatio (NMF) in Micro Array Gene Expression Data Analysis. Await is a list of classic references in this area.
4. Hidden Markov Models applied to miRNA studies.
5. Chaos Game Representation of Bio-sequences
Please see the publications link in my home page to see research publications of myself and my doctoral students. Also download some helpful documentation on research:
(i) On Becoming a Researcher
(ii) Checklist for Submitting Research Papers.
The following candidates have been awarded PhD by University of Kerala, under my supervision/co-supervision:
5. Dr. Jayasudha J.S.
Web Caching & Prefetching Techniques for Web Traffic/Latency Reduction, 2008.
4. Dr. S. Sreenadhan
Coding Measures for Locating Exons in Genomes using Signal Processing, 2007.
3. Dr. T. Mahalakshmi
Visualisation of Genomic Data, 2007.
2. Dr. Mini Idiculla
Computational Electromagnetic studies on Claw Pole Alternators, 2006.
1. Dr. Bindu G.R.
Computational Electromagnetic studies on Train Lighting Alternators, 2005.
The following candidates have submitted their thesis:
1. Deepa Gopinath
Malayalam Text-to-Speech System - Duration Modelling (CDIT), 2008.
2. Sheeja M.K.
Holographic Data Storage (CDIT), 2008.
The following candidates are in various stages of research (Research centre in brackets, CBI is Centre for Bioinformatics, CET is Trivandrum Engineering College)
1. Koshy Vaidyan, TCS (CET)
2. Smitha Dharan, IHRD (CBi)
3. Vinod Chandra S.S., CET (CBi)
4. Betsy Sheena Cherian (CBi)
5. Gopakumar G., (CBi)
6. Sr. Lissy Anto, St.Joseph's College, Irinjalikkuda (CBi)
7. Prof. Vrinda V. Nair, GEC, Trichur (CBi)
8. Sanu Thomas, MG University (CBi)
Awaiting Registration:
9. Geetha, SCTIMST (CBi)
10. Saritha Nampoothiri, V.T.B. College, Palakkad (CBi)
11. Lijo Anto (CBi)
I currently teach the following courses for MPhil Bioinformatics, in addition to some general courses:(The MPhil brochure is available here and the syllabus here).
* Genomics: Past Exam Paper
* Proteomics & Computer Aided Design Past Exam Paper
* Applied Bioinformatics Past Exam Paper
* MSc. Computational Biology - Syllabus
* Intoroduction to Computational Biology - A Tutorial